Are we on the cusp of a “5th wave”? Will Thanksgiving prove to be a super-spreader event? Vaccine efficacy wanes—are boosters the answer? Mandates stall—is a more nuanced approach taking into consideration natural immunity a better path? Antiviral pills and better therapeutics on the way for 2022; Testing options need to be expanded; New studies underscore benefits of lifestyle, diet and supplements in supporting immune resiliency; Over 1 million Americans may have permanent loss of taste and smell in wake of Covid; Minimizing risk of transmission on plane flights; What is viral “shedding” and how does the vax impact it? Is diabetes associated with joint pain?