Children's Hospital Of Pittsburgh's Pediatric Hospital Medicine Podcast

Title: Chronic Lyme - Is This a Thing? Target Audience This activity is directed to physicians, medical students, nurse practitioners, nurses, and physician assistants. Objectives: Upon completion of this activity, participants should be able to: Review the definitions of Chronic Lyme vs Infection Associated Chronic Illness vs Lyme Associated Chronic Illness vs Post Treatment Lyme Disease Syndrome (PTLDS).   Discuss epidemiology and incidence of Lyme infections in the USA.   Discuss in detail the PTLDS and how it’s defined and what the literature says about diagnosis and treatment.     Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. No relationships with industry relevant to the content of this educational activity have been disclosed. Andrew Nowalk MD, PhD — Associate Professor, Department of Pediatrics, Uni

Title: Journal Club Series Episode 14- Cost Benefit, Cost Effectiveness, and Outcomes Target Audience This activity is directed to physicians, medical students, nurse practitioners, nurses, and physician assistants. Objectives: Upon completion of this activity, participants should be able to: •      Evaluate cost-benefit analyses and their impact on patient outcomes. •      Analyze cost-effectiveness studies and their influence on patient outcomes.   Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. No relationships with industry relevant to the content of this educational activity have been disclosed. Lynsey Vaughan, MD — Assistant Professor, Department of Pediatrics, University of Texas at Austin, Dell Medical School No relationships with industry relevant to the content of this educational activity have been disclosed. Con

Title: Journal Club Series Episode 13-  Systematic review and meta-analysis Target Audience This activity is directed to physicians, medical students, nurse practitioners, nurses, and physician assistants. Objectives: Upon completion of this activity, participants should be able to: •      Conduct systematic reviews and apply proper methodologies. •      Perform meta-analyses and utilize appropriate techniques.  Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. No relationships with industry relevant to the content of this educational activity have been disclosed. Mary Lou Klem PhD, MLIS — Assistant Director for Advanced Information Support, University of Pittsburgh School of Medicine, Health Sciences Library System No relationships with industry relevant to the content of this educational activity have been disclosed. Confli

Title: Journal Club Series Episode 12- Regression (eg, linear, logistic, survival analysis) Target Audience This activity is directed to physicians, medical students, nurse practitioners, nurses, and physician assistants. Objectives: Upon completion of this activity, participants should be able to: •      Describe the concept of regression. •      Differentiate between linear and logistic regression. •      Interpret survival analysis.  Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. No relationships with industry relevant to the content of this educational activity have been disclosed. Jenna Carlson Ph.D — Assistant Professor of Human Genetics and Biostatistics, University of Pittsburgh No relationships with industry relevant to the content of this educational activity have been disclosed. Conflict of Interest Disclosure:

Title: Journal Club Series Episode 11- Measurement of association and effect (eg, correlation & causation) Target Audience This activity is directed to physicians, medical students, nurse practitioners, nurses, and physician assistants. Objectives: Upon completion of this activity, participants should be able to:      Review measurement of association and effect.      Review relative risk & Odds ratio.  Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. No relationships with industry relevant to the content of this educational activity have been disclosed. Matthew Wilkinson MD, MPH - Associate Professor, Department of Pediatrics, The University of Texas at Austin Dell Medical School Dr. Wilkinson discloses that he is a consultant for Koru Medical and is a stockholder with EM Device Lab. Conflict of Interest Disclosure

Title: Journal Club Series Episode 10- Measurement of association and effect (relative risk & odds ratio) Target Audience This activity is directed to physicians who take care of hospitalized children, medical students, nurse practitioners, and physician assistants working in the emergency room, intensive care unit, or hospital wards. Objectives: Upon completion of this activity, participants should be able to: 1.      Review measurement of association and effect. 2.      Review relative risk & Odds ratio.  Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. No relationships with industry relevant to the content of this educational activity have been disclosed. Matthew Wilkinson MD, MPH - Associate Professor, Department of Pediatrics, The University of Texas at Austin Dell Medical School Dr. Wilkinson discloses that he

Title: Journal Club Series Episode 9 - Common statistical tests Part 2 (eg,  Student’s T test, analysis of variance [ANOVA], chi-square, nonparametric tests)  Target Audience This activity is directed to physicians who take care of hospitalized children, medical students, nurse practitioners, and physician assistants working in the emergency room, intensive care unit, or hospital wards. Objectives: Upon completion of this activity, participants should be able to: 1.      Review common statistical tests 2.      Review Student’s T test, analysis of variance [ANOVA]. 3.      Review chi-square vs nonparametric tests). Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. No relationships with industry relevant to the content of this educational activity have been disclosed. Philana Lin M.D., MSc, -- University of Pittsburgh School of

Title: Journal Club Series Episode 8 - Common statistical tests Part 1 (eg,  Student’s T test, analysis of variance [ANOVA], chi-square, nonparametric tests)  Target Audience This activity is directed to physicians who take care of hospitalized children, medical students, nurse practitioners, and physician assistants working in the emergency room, intensive care unit, or hospital wards. Objectives: Upon completion of this activity, participants should be able to: 1.      Review common statistical tests 2.      Review Student’s T test, analysis of variance [ANOVA]. 3.      Review chi-square vs nonparametric tests).   Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. No relationships with industry relevant to the content of this educational activity have been disclosed. Philana Lin M.D., MSc, -- University of Pittsburgh Sch

Title: Journal Club Series Episode 7- Statistical Power Target Audience This activity is directed to physicians who take care of hospitalized children, medical students, nurse practitioners, and physician assistants working in the emergency room, intensive care unit, or hospital wards. Objectives: Upon completion of this activity, participants should be able to: 1.      Review Statistical power in research, when to use it and how to interpret it.   Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. No relationships with industry relevant to the content of this educational activity have been disclosed. Matthew Wilkinson MD, MPH - Associate Professor, Department of Pediatrics, The University of Texas at Austin Dell Medical School Dr. Wilkinson discloses that he is a consultant for Koru Medical and is a stockholder with EM Devi

Title: Episode 6- Hypothesis Testing (e.g. Type 1 and Type II Errors, P-values) Target Audience This activity is directed to physicians who take care of hospitalized children, medical students, nurse practitioners, and physician assistants working in the emergency room, intensive care unit, or hospital wards. Objectives: Upon completion of this activity, participants should be able to: 1.      Discuss the definition and relevance of p-values. 2.      Discuss type 1 vs type ii errors. 3.      Discuss statistical significance and what it means.   Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. No relationships with industry relevant to the content of this educational activity have been disclosed. Jenna Carlson Ph.D. - University of Pittsburgh- Assistant Professor of Human Genetics and Biostatistics in school of Public Hea

Title: Episode 5 - Bias and Confounding Target Audience This activity is directed to physicians who take care of hospitalized children, medical students, nurse practitioners, and physician assistants working in the emergency room, intensive care unit, or hospital wards. Objectives: Upon completion of this activity, participants should be able to: 1.      Review bias in research. 2.      Review confounding in research. Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. No relationships with industry relevant to the content of this educational activity have been disclosed. Rebekah Miller MLIS - University of Pittsburgh School of Medicine - Research & Instruction Librarian No relationships with industry relevant to the content of this educational activity have been disclosed. Conflict of Interest Disclosure: No other plann

Title: Episode 4- Incidence, prevalence & Study Definitions Target Audience This activity is directed to physicians who take care of hospitalized children, medical students, nurse practitioners, and physician assistants working in the emergency room, intensive care unit, or hospital wards. Objectives: Upon completion of this activity, participants should be able to: 1.      Review incidence in research. 2.      Review prevalence in research. 3.      Review screening and how it pertains to research. Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. No relationships with industry relevant to the content of this educational activity have been disclosed. Philana Lin M.D. MSc - University of Pittsburgh School of Medicine - Associate Professor in the Department of Pediatrics - Pediatric Infectious Disease Division Dr. Lin

Title: Episode 3b- Types of variables & Distribution of data Target Audience This activity is directed to physicians who take care of hospitalized children, medical students, nurse practitioners, and physician assistants working in the emergency room, intensive care unit, or hospital wards. Objectives: Upon completion of this activity, participants should be able to: 1.      Review the types of variables (eg, continuous, ordinal, nominal). 2.      Review the distribution of data (eg, mean, standard deviation, skewness). 3.      Review how the types of variables and the distribution of data interact in research. Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. Philana Lin M.D. MSc - University of Pittsburgh School of Medicine - Associate Professor in the Department of Pediatrics - Pediatric Infectious Disease Division C

Title: Episode 3a - Measurements (ex: reliability and validity) Target Audience This activity is directed to physicians who take care of hospitalized children, medical students, nurse practitioners, and physician assistants working in the emergency room, intensive care unit, or hospital wards. Objectives: Upon completion of this activity, participants should be able to: 1.      Review measurements in a study. 2.      Review validity in research. 3.      Review reliability in research. Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. Philana Lin M.D. MSc - University of Pittsburgh School of Medicine - Associate Professor in the Department of Pediatrics - Pediatric Infectious Disease Division Conflict of Interest Disclosure: No other planners, members of the planning committee, speakers, presenters, authors, content reviewer

Title: Episode 2- Study Design, Performance, Analysis and Generalizability Target Audience This activity is directed to physicians who take care of hospitalized children, medical students, nurse practitioners, and physician assistants working in the emergency room, intensive care unit, or hospital wards. Objectives: Upon completion of this activity, participants should be able to: Review Study design. Review Performance and analysis. Review generalizability vs internal validity.   Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. Jenna Carlson Ph.D. - University of Pittsburgh- Assistant Professor of Human Genetics and Biostatistics in school of Public Health Rebekah Miller MLIS - University of Pittsburgh School of Medicine - Research & Instruction Librarian Conflict of Interest Disclosure: No other planners, member

Title: Episode 1- Diagnostic tests (eg, sensitivity and specificity, predictive values, disease prevalence) Target Audience This activity is directed to physicians who take care of hospitalized children, medical students, nurse practitioners, and physician assistants working in the emergency room, intensive care unit, or hospital wards. Objectives: Upon completion of this activity, participants should be able to: 1    Review sensitivity and specificity.      Review predictive values. 3   Review disease prevalence vs incidence. Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. Philana Lin M.D., MSc, -- University of Pittsburgh School of Medicine - Associate Professor in the Department of Pediatrics - Pediatric Infectious Disease Division Conflict of Interest Disclosure: No other planners, members of the planning committee, s

This is the introduction to our journal club series. The next 14 episodes after this will discuss important and relevant topics in biostatistics, helping you understand and critically evaluate scholarly activity. To create these episodes we partnered with our good friends at University of Texas at Austin, Dell Medical School. This introductory episode is just me talking so there’s no CME attached to it. Our apologies for that. We hope you enjoy.

Title: Adrenal Insufficiency Target Audience This activity is directed to physicians who take care of hospitalized children, medical students, nurse practitioners, and physician assistants working in the emergency room, intensive care unit, or hospital wards. Objectives: Upon completion of this activity, participants should be able to: Review symptoms and pathophysiology of primary vs secondary adrenal insufficiency.   Review management of both primary and secondary adrenal insufficiency.   Review workup of both primary and secondary adrenal insufficiency and review adrenal crisis.   Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine. Selma Witchel MD- Professor Pediatrics, University of Pittsburgh School of Medicine Maria G. Vogiatzi MD - Professor of Pediatrics, Children's Hospital of Philadelphia, U

Title: Physician Suicide Target Audience This activity is directed to physicians who take care of hospitalized children, medical students, nurse practitioners, and physician assistants working in the emergency room, intensive care unit, or hospital wards. Objectives: Upon completion of this activity, participants should be able to: 1.      Review the epidemiology of Physician Suicide. 2.         Review the rates of physician suicide in comparison to general population. 3.         Review factors that are specific to increase the risk of physician suicide. Faculty:  Planning Committee: Allison Williams MD, — Assistant Professor of Pediatrics, Division of Pediatric Hospital Medicine, UPMC Children's Hospital of Pittsburgh Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center (UPMC.) Paul C. Gaffney Division of Pediatric Hospital Medicine Dr. Tarchichi has disclosed he was a member of th

This episode was made in partnership with the AAP SOHM Newborn Hospitalist Subcommittee   Title: Ankyloglossia and Breastfeeding- New Clinical Report Review Target Audience This activity is directed to physicians who take care of hospitalized children, medical students, nurse practitioners, and physician assistants working in the emergency room, intensive care unit, or hospital wards. Objectives: Upon completion of this activity, participants should be able to: Review the new clinical report on identification and management of ankyloglossia and its effect on breastfeeding in infants.   Review the diagnosis of ankyloglossia.   Review breastfeeding physiology.   Faculty:  Planning Committee: Allison Williams MD, — Assistant Professor of Pediatrics, Division of Pediatric Hospital Medicine, UPMC Children's Hospital of Pittsburgh Course Directors: Tony R. Tarchichi MD — Associate Professor, Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Cen