Inside Health

What goes into our flu vaccine always has an element of guesswork. Usually the experts get it right but sometimes nature has other ideas and a new strain emerges. Dr John McCauley, Director of the Worldwide Influenza Centre at the Francis Crick Institute in London tells Dr Mark Porter about Aussie flu and how different flu strains pose risks to different groups of people. Cow's milk allergy is the most common food allergy among infants and it affects at least one in 50 babies, toddlers and pre-school children in the UK. It's an allergic reaction to the protein in cow's milk. There are two different types though and one type, called delayed cow's milk allergy, is often missed by health care professionals because it's easily confused with other common conditions. Lucy Wronka tells Inside Health her baby son George was ill for months with reflux, eczema and an upset stomach. It was only a chance meeting with a friend who recognised the symptoms that led to a diagnosis of delayed cow's milk allergy. Twenty four h

Can dogs smell cancer? Ever since Hippocrates the odour of disease has been used to aid diagnosis but has this simple technique been forgotten? Dr Mark Porter investigates the evidence for whether canine super noses can be used to accurately detect cancer. There have been plenty of anecdotes reported but what about hard science? Studies since 2004 from the Medical Detection Dogs Centre in Milton Keynes have shown convincing results and they've now teamed up with MIT in the US, specialists in 'e-noses'. Could devices the size of a mobile phone be used to sniff for disease?

The Chief Medical Officer has warned of a "post-antibiotic apocalypse" and "the end of modern medicine". As antibiotic resistance increases, the options to treat potentially deadly infections reduces. Inside Health's Dr Margaret McCartney discusses the latest campaign by Public Health England to remind us all not to take antibiotics when they're not needed.It's been over thirty years since there was a breakthrough in the treatment of pneumonia, but that could soon change....and from an surprising source. Researchers in Birmingham at Queen Elizabeth Hospital have been working with the cholesterol-lowering drugs, statins, and discovered that this medication can turbo-charge our immune systems, helping us to fight infection. Dr Liz Sapey, respiratory consultant and researcher tells Dr Mark Porter about the exciting possibility of tablets that cost just a few pence each, being used to treat potentially deadly lung infections like pneumonia. Epilepsy is normally controlled by anti-seizure medication but for a thir

GPs have been told to ask about their patients' sexual orientation as NHS England plans to record this data for everyone using the service over the age of 16. Dr Google - are doctors' noses really being put out of joint by patients searching their symptoms on the internet to come up with their own diagnoses? Hypermobility is being double jointed and flexible and is often perceived as an asset, but for around 1 in 30 of the population it can be a problem that is often missed - and mismanaged. Plus a counterintuitive approach to help people with Chronic Obstructive Pulmonary Disease. You might think the last thing someone with breathing difficulties needs is smaller lungs, but lung reduction surgery is exactly what's being offered some people with COPD.

Vaginal mesh, used for the treatment of prolapse and incontinence, has hit the news recently as women pursue litigation after suffering serious complications. But there have been concerns ever since the first type of vaginal mesh was launched in the mid-nineties, only to be withdrawn a few years later. Carl Heneghan, Professor of Evidence Based Medicine at the University of Oxford, explains the 'shambolic' regulation of medical devices, Consultant gynaecologist Swati Jha, who has been collecting data on mesh for over a decade, believes media coverage has been muddled. Women speak of living with surgery, while Inside Health's Dr Margaret McCartney calls for a registry to collect effective data. Plus, new guidance in Scotland challenges the so called 'J-shaped curve' - evidence that moderate drinking is good for the heart. Naveed Sattar, Professor of Metabolic Medicine at the University of Glasgow and part of the committee that produced the updated guidance, talks to Mark Porter about the changes.

Mention arthritis and most people think of older people with osteoarthritic hips or knees. But children get arthritis too, although it's an inflammatory condition where the child's immune system attacks the lining of the joints causing pain, swelling and stiffness. But the joints aren't the only part of the body affected. Around one in six of the 12,000 children in the UK with juvenile idiopathic arthritis also develop worrying inflammation in their eyes, uveitis. This is a silent, symptomless condition which can result in significant visual impairment and even blindness. But a new drug treatment, tested in the UK, has proved to be so successful for this group of children that it has revolutionised treatment both in this country and around the world. The benefits were so large that the trial was stopped early and the new therapy adopted as frontline treatment. Dr Mark Porter visits the Bristol Eye Hospital and meets paediatric rheumatology consultant, Professor Athimalaipet Ramanan to find out more.Bigger ba

After Simon Cowell paid for a Britain's Got talent contestant to have surgery in the US for her curved spine we examine the state of therapy for scoliosis here in the UK. Recent headlines claimed that 1 in 4 teenage girls are depressed but were they accurate? And pets in hospital: the Royal College of Nursing has called for patients to have better access to animals, including their own. Plus Eustachian tubes: tips for what to do if you have blocked ears after your summer holiday.

Inside Health reveals the poor state of addiction services in England with heroin and morphine related deaths the highest on record. Professor Colin Drummond raises concerns about a split in care between the NHS and Local Authorities since the 2012 Health and Social Care Act. And personal testimony is heard from Alison Bedford Russell whose son George died of a heroin overdose last year. The Care Quality Commission, who is responsible for inspections, has found that 2/3 residential drug and alcohol treatment services failed to meet the required standard. Dr Paul Lelliott, Deputy Chief Investigator of hospitals at the CQC, explains what was discovered.The correct use of medical language is a topic close to Inside Health so Margaret McCartney was naturally drawn to discuss news this week about the misuse of the term Schizophrenia.And as London hosts the first ever Cardio-Oncology Summit in Europe, specialists from both fields discuss how to treat and prevent heart problems in people undergoing therapy for cance

Breast Density - the major risk factor for breast cancer that you may have never heard of. Health Education - a long term approach to changing attitudes to illness by encouraging children to be less dependent on doctors and pills. Switching Outcomes - one reason why so few clinical trials result in real changes in practice that benefit patients.

Margaret McCartney unpicks recent headlines suggesting its okay not to finish your antibiotics; Lung Cancer screening in the high risk; Can you die a broken heart? Evidence suggests this is a real condition called Takotsubo syndrome and is much more common than previously thought. And gender bias in trials.

There are growing concerns about the widespread use of PPIs, the acid suppressing family of drugs used to treat indigestion and the most prescribed in the world. They are recommended to be used for weeks in typical cases of heartburn, but most people including Mark, take them for months or years. But one reason why PPIs are being used so widely is to protect the lining of the gut from aspirin and combining these two drugs may also have benefits against cancer. Mark hears preliminary findings on the so called chemo-protective effects of aspirin. And radiotherapy is a crucial part of modern cancer treatment so why does it get so little attention compared to drugs? Plus why radiation and smoking are particularly poor bedfellows.

The Hepatitis B vaccine has been added to the childhood national programme joining the 5 vaccines already given to all young babies at 8, 12 and 16 weeks. Andrew Pollard, Professor of Paediatric Infection & Immunity at the University of Oxford, and Chair of the Joint Committee on Vaccination and Immunisation, explains why.Margaret McCartney and Mark Porter visit men in north London looking for the physical and mental benefits of community sheds. The obesity paradox - can being overweight sometimes be beneficial? Gavin Murphy, British Heart Foundation Professor of Cardiac Surgery at the University of Leicester and Naveed Sattar, Professor of Metabolic Medicine at the University of Glasgow, debate the latest research suggesting that obese people are more likely to survive heart surgery than their slimmer peers. Are clinical trials good for you? We examine the evidence behind conventional wisdom that people taking part in research tend to fare better - whatever their illness.

Are we on the cusp of a new era where computers rather than doctors will be doing the diagnosing. Ali Parsa, founder of Babylon Health, believes we are and is developing an online tool using artificial intelligence that diagnoses quicker and more accurately than a doctor. He debates the issues with resident sceptic Dr Margaret McCartney. Mark Porter visits the world's first national tissue bank for pancreatic cancer, set up to aid research into a disease that has seen no outcome improvement for over 40 years. Plus statins and muscle aches; could the drugs' bad press in the media actually increase the odds of people experiencing side effects - the so called nocebo effect?

Price rises of everyday medicines due to some manufacturers utilising monopolies; Can a simple routine blood test help identify cancer; A definitive guide on undescended testes with evidence for the best time to intervene if a baby boy's testes do not drop and the downsides of delay; Aspirin and the risk of stomach bleeds in the elderly.

Statins have dominated the cholesterol-lowering field for some years but last week the results of an international trial of Evolocumab, one a new breed of medicines for reducing cholesterol, was hailed as a breakthrough. Professor Peter Sever, one of the leaders of the trial, explains how Evolocumab differs from statins and Dr Margaret McCartney takes a look at the trial.You may have noticed them in work places, gyms, and other public spaces but do you know how and when to use a defibrillator? Every time someone has a cardiac arrest and CPR is performed we should also be running for the nearest defibrillator. But currently this only happens in 2-3% of cardiac arrests, putting thousands of lives at risk every year. Mark speaks to teacher Erica Melsom and the pupil, Alex Cowes, whose life she saved by using the school defibrillator. Professor Gavin Perkins explains why and when we should run and get one. And Mark demonstrates just how simple they are to use, even if you've never touched one before.Posttraumatic

Clarification of new evidence that Bisphosphonates for osteoporosis may actually weaken bones if people are left on them for too long ; Dietary change using FODMAPS to treat Irritable bowel syndrome when medicines have not worked; CRP testing for chest infections to identify which need antibiotics; And Mark eats humble pie for getting clinical terminology mixed up.

More than 6500 people are currently on the national transplant waiting list, hoping for an organ to be donated which might save their lives. Many of them will wait for years and, sadly, hundreds will die before a suitable organ becomes available. The low supply of organs remains the main restriction on performing lifesaving transplant surgery. The British Medical Association believes that moving to an opt-out donation system - where people who die without expressing whether or not they wish to donate their organs will be presumed to be willing to donate - would increase donation rates and save lives. The system has been in place in Wales since December 2015 and now the BMA says it's time the rest of the UK followed the Welsh model. Dr Margaret McCartney discusses with Dr Phil Banfield, chair of the British Medical Association Welsh Council. An area of medicine not often discussed on Inside Health is pathology. Mark visits the morgue at St Mary's Hospital in London to speak to pathologist Mike Osborn. What hap

New moves to test pregnant women for smoking by measuring carbon monoxide on their breath. How helpful are lifestyle targets like 10 portions of fruit and veg or 10, 000 steps a day? The incidence of thyroid cancer has tripled in 40 years, but many of the tumours picked up are on scans for something else and may never have caused harm. Mark Porter debates the issues. Plus this week's uncertainty question for Margaret McCartney and Carl Heneghan, to floss or not to floss?

Vitamin D , the sunshine vitamin, has been in the news again with claims that supplements could help ward off coughs , colds and flu. Dr Margaret McCartney takes a look at the study that generated the headlines.Whether or not a severely injured person will receive blood products at the scene of an accident depends on which air ambulance service they are attended by: some air ambulances replace lost blood with red blood cells, but others replace only with saline solution. Evidence from military casualties in Afghanistan suggests giving blood before patients reach hospital leads to better survival rates, but evidence from civilian populations in the UK is less clear. A new randomised controlled trial, being conducted by six air ambulance services, will investigate which course of action has the best outcomes for patients. Mark visits the Midlands Air Ambulance to hear more from lead investigator and trauma anaesthetist Dr Nick Crombie and critical care paramedic Jim Hancox.Phantom limb pain - pain in an amputat

A special debate on the current state of the NHS. Recorded in front of an audience at the BBC Radio Theatre London.The last few months have seen the service creaking under unprecedented demand, and there is likely to be worse to come. Something needs to give. Is it simply a matter of more resources, or do we also need to change our expectations of what the NHS provides? Is rationalisation and rationing the way forward?Dr Mark Porter discusses the issues with a panel including Clare Marx, president of the Royal College of Surgeons, Chris Hopson, chief executive of NHS Providers, David Haslam, chair of NICE, Prof Sir Nick Black, London School of Hygiene and Tropical Medicine and regular contributor Margaret McCartney GP. Issues discussed include whether the NHS should continue to be free at the point of use. Is there too much bureaucracy with too many bosses? Was the internal market evidence based, has it worked and was it fair? Rationing of treatments. And can the NHS be taken out of politics? Inside Health li