Fx Medicine Podcast Central

A Closer Look at COMT and CBS Genes with Annalies Corse

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Sinopsis

The accessibility of genetic testing is on the rise, with a range of testing services now available world-wide. Although our genes are the scaffold from which we are fundamentally built, genes are not as black and white as we're led to believe. They're simply one layer of the onion, or one piece of a very large puzzle and by all accounts, this area of science is still quite new. The genes which encode for two important enzymes, catechol-O-methyltransferase (COMT) and cystathionine beta-synthase (CBS) are vital for healthy catecholamine, catechol estrogens, several drugs and homocysteine metabolism. They have been implicated in a range of health issues ranging from decreased fertility and pre-eclampsia to behaviour and mood issues, even cancer. Today we are joined by medical scientist and naturopath, Annalies Corse, to tackle not only what the clinical relevance of these genes are, but Annalies and Andrew dive deep into the ethics and relevance of SNP testing and whether it alters the course of therapeutic int