Medical Industry Feature

From Heterogeneity Comes New Insights: Exploring the Role of T Cells & OX40 Signaling in Atopic Dermatitis

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Sinopsis

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Jonathan Silverberg, MD, PhD, MPH Atopic dermatitis is more than a disease of the skin. It’s a complex and heterogeneous inflammatory disease mediated by multiple T-cell–driven inflammatory pathways, like the OX40 pathway, leading to chronic and persistent symptoms and significant burden.1-4 Explore the heterogeneity of atopic dermatitis and the importance of OX40 signaling in disease pathogenesis with Dr Charles Turck and Dr. Jonathan Silverberg, Professor and Director of Clinical Research and the Director of Patch Testing at George Washington University School of Medicine and Health Sciences. References: Silverberg JI. Clinical Management of Atopic Dermatitis. 1st ed. 2018. Ratchataswan T, et al. J Allergy Clin Immunol Pract. 2021;9:1053-1065. Weidinger S, et al. Nat Rev Dis Primers. 2018;4:1. De Bruyn Carlier T, et al. J Autoimmun. 2021;120:102634. ©2023 Amgen Inc. All rights reserved. USA-451-80031 8/23